Tag: antidepressants

Depressed People Who Take Antidepressants Do Better Long-Term – Part 2

As I mentioned last week, it’s very difficult to measure long-term outcomes of depression treatment due to the confounding depression variables like severity of depression, duration of depression, number of depressions and so on.

In short, the sicker you are, the more depressed you are, the more likely it is you’ll get treatment.

Antidepressant Treatment Outcomes Long-Term, A Study

I discussed the basic outcomes of this study: The association between antidepressant use and depression eight years later: A national cohort study by Colman et al. which tries to take these variables into account.

Colman et al. showed those who took antidepressants had better depression treatment outcomes than those who didn’t, eight years later, once confounding variables were taken into consideration.

I’ll now point out the strengths and weaknesses of this study as well as some other interesting tidbits shown or cited in the study. Oh, and I’ll give my opinion on what it all means.

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Depressed People Who Take Antidepressants Do Better Long-Term

Recently the controversy over long-term outcomes of those who use psychotropic medication has flared up again. Some people argue depression/bipolar/mental illness patients do the same, or better, when they don’t take psychiatric medications long-term. However, the statistics they use to assert this claim are often faulty.

A study from Calgary, Alberta, Canada (yes, we do research up here too) has attempted to fix some of the bias seen in other long-term depression treatment outcome statistics. I’ll cut to the chase for you:

Over the course of eight years people with depression who took antidepressants had better outcomes.

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How To Get Off Pristiq or Reduce Pristiq

Now I’m not a doctor, in fact, I don’t even play one on TV, but I wanted to share a little about me and how I’m handling getting off of, or at least reducing, Pristiq.

Please also read: When to Get Off Antidepressants with Bipolar Disorder

Antidepressant Pristiq – Easy On, Not-So-Easy Off

I’ve been talking the antidepressant Pristiq (desvenlafaxine) for months and it doesn’t seem to be doing much, but honestly, the withdrawal from Pristiq is so bad I didn’t want to attempt getting off of it. As you might know, Pristiq is a metabolite of Effexor and Effexor, another antidepressant, is also a nightmare to get off of. If I would miss a Pristiq dose by even a few hours I would become suicidally depressed. Really. No joke.

No Taper Strategy for Pristiq

So getting off of Pristiq wasn’t on my short list of fun things to do. There is no taper strategy for Pristiq as it only comes in 50 mg and 100 mg tablets and you cannot cut them.

How I’m Getting Off Pristiq

But I seem to be successfully reducing the dose of Pristiq with minimal impact and withdrawal.

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I write a three-time Web Health Award winning column for HealthyPlace called Breaking Bipolar.

Also, find my writings on The Huffington Post and my work for BPHope (BP Magazine).

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