Antidepressant Comparison: Are Pristiq and Effexor the Same?

Posted by Natasha Tracy | Jun 18, 2010

Does Pristiq Just Serve to Extend the Effexor Patent?

If you live in the US, you’ve probably seen all the commercials for the new and pastel-pink-coloured antidepressant Pristiq. (Yes, prescribed for depression.) Pristiq is new and has a huge marketing push behind it and is a selective serotonin norepinephrine reuptake inhibitor (SNRI) antidepressant. In other words, it’s an antidepressant that works on both serotonin and norepinephrine neurotransmitters. It is not the only antidepressant to do this, but SNRIs are a smaller class of drugs than those that just effect serotonin alone (like Prozac). (Although admittedly, there seems to be a suspicious number of SNRI antidepressants in development.)

Pristiq and Effexor Are Almost the Same Drug

What you might not know, is the same company that makes the drug Pristiq (Wyeth) also makes Effexor, which is an almost identical antidepressant, and Effexor has recently become available in generic form (Venlafaxine). Pristiq, O-desmethylvenlafaxine, is actually the main metabolite of Effexor, venlafaxine hydrochloride.

This means that if you take Effexor, your body breaks it down into Pristiq and other chemicals. Yes, Pristiq and Effexor are almost the same drug.

Depression: Why Do People Keep Asking What Happened?

Posted by Natasha Tracy | Jun 16, 2010

I have had this exchange a thousand times,

“I’m really depressed.”
“Why, what happened?”

Have you been missing the plot?

Bipolars Get Depressed

Bipolar disorder is defined as the cycling of moods between a depression and a mania, or hypomania. It is not characterized by being cut off in traffic and then being depressed about it.

I’m Damaged. I’m Bipolar. Love Me. Save Me.

Posted by Natasha Tracy | Jun 14, 2010

Last night I watched Crazy for Love a very bad movie wherein a man, Max, is put into a mental hospital for attempting suicide for the tenth time. When he’s there, he glimpses a very ill, schizophrenic, Grace, whereupon he instantaneously falls in love with her. She too is determined to kill herself. His life’s mission then is to “make her better”. To “make her happy”. Having found his new mission in life, he no longer wants to kill himself.

Well, pin a rose on his nose.

Are Bipolars Crazy? I Am. It’s Okay to Be Crazy.

Posted by Natasha Tracy | Jun 10, 2010

I am crazy. I tell this to people in my personal life. It’s not a secret. I figure there’s no point in trying to cover it up; it’ll come out eventually. I’m crazy. The approximately 20 scars on my forearms rather give away that something is amiss.

But people really don’t like the word “crazy”. In fact, most often, what people say to me is, “no, you’re not!”. Well, actually, I am. I have a mental illness, I’m bipolar and I’m crazy.

more at Breaking Bipolar: Are bipolars crazy. I am.

Bipolar Natasha Tracy’s Interview with HealthyPlace

Posted by Natasha Tracy | Jun 9, 2010

Here is today’s interview with me, Natasha Tracy, complete with call-in questions. I think it went well. We discussed some of the negative impact bipolar has had on my life. I talked about bipolar disorder, depression, suicide, coping and how my writings at HealthyPlace have been controversial.

Self-Harm: Stabbing Yourself is Bad

Posted by Natasha Tracy | May 28, 2010

Stabbing is bad. It just is. If you have to pick self-harm options between cutting, hitting, and stabbing, don’t pick stabbing.

Unless you’re trying to kill someone, in which case I think stabbing would be pretty good. And satisfying. I’m surprised more murderers don’t pick stabbing.

Anxiety, Impulse Control Self-Harm and Stabbing

I’m having anxiety issues. And impulse control issues. And stabbing issues. Well, that last one is really a function of the other two, but it’s an issue nonetheless.

I’ve always been attracted to stabbing. I think that’s because when you start wielding a blade with force, you can’t change your mind. And it’s so easy to did deep. And draw a lot of blood.

Depression: Silence of Being Ignored Feels Like Loss

Posted by Natasha Tracy | May 14, 2010

This silence feels familiar. I despise the deafening, familiar sounds of silence. They terrify me. I suppose the silence strangles me. Strangled, alone, screaming.

I Hate Being Ignored

People who know me, know this about me. They know how much I hate being ignored. They know that when they don’t return my calls or my emails my mind riles in negative and catastrophic scenarios. People who actually like me don’t want to do that to me.

Will ECT Work for Me? — Predictors of ECT Efficacy

Posted by Natasha Tracy | May 12, 2010

It would be nice to know ahead of time, if a treatment would work. Unfortunately, no one cal tell the future: not for cancer treatment and not for mental illness treatment like electroconvulsive therapy (ECT) either.

Will Electroconvulsive Therapy Work for Me?

But very smart people try to figure out what might predict the outcome of treatments. Especially treatments like ECT, a hotly debated, and much maligned treatment. That’s the good news. And the bad news.

In a retrospective chart review of depressive and bipolar patients in a Netherlands hospital, of those who received ECT, 65.8% met the standards for remission. The only predictor of response found was duration of index series.

People Who Attempt Suicide Don’t Want to Die

Posted by Natasha Tracy | May 7, 2010

There are frequent reports that of the people who survive suicide attempts, they realized sometime after the pills, or the gun, or the jump, they didn’t want to die. This is obvious. No one wants to die. People who attempt suicide don’t want to die. They want to be out of pain.

People Who Attempt Suicide Don’t Want to Die, They Want to Be Free of Pain

It is obvious that every human wants to live. No matter what their personal circumstance each human claws against death until they either don’t see it coming, or they feel there is no alternative for them.

Many people actually have no problem with that – we call it doctor-assisted suicide. The reason it’s “OK” to kill yourself near the end of your life is because it is medically certain you will be in agony for the short remainder of your existence. In this instance doctors just turn their head while a little extra morphine is administered. Happens all the time.

Bipolar (Mental Illness in General) Isn’t Considered a Terminal Illness

No one, however, recognizes mental illness as a terminal illness. It can never be determined to a medical certainty that the rest of your life will be lived in agony. Even though it might be. Tomorrow might be different. Magic might happen. A unicorn might walk through my front door. But probably not. Tomorrow is probably going to be exactly like today. Only it’ll be Saturday. Yay.

Depression Deprives People of Pleasure, Causes Pain

The problem with a disorder like depression is that pleasure is simply absent. Pleasure in all ways is gone. Desire is gone. Depressed people don’t like anything. Depressed people don’t want to do anything. And even if something extraordinary were to happen, like a unicorn in your living room, it wouldn’t matter. Because the ability to feel pleasure is gone.

And if anhedonia weren’t enough to make life absolutely pointless, there’s the adding of pain on top of it. Pain on top of pain on top of the unbearable, unarguable knowledge of more pain. And still, the fact is, I don’t want to die. I just really don’t want to live. Like this.