Tag: medication

Hope for Treatment-Resistant Bipolar Depression

Recently, I wrote a piece for PsychCentral that outlined some recommendations for treatment-resistant bipolar disorder. This piece talked about first-line and second-line agents for the treatment of bipolar disorder but I wanted to delve a little further into the novel agents that are now being studied for the treatment of bipolar depression. These are medications that are not typically used to treat bipolar disorder, work in new ways and show promise in recent studies. This is cutting edge and if you’re treatment-resistant this is an area that can offer you hope.

Why Are Novel Agents Needed in the Treatment of Bipolar Depression?

The reason why this piece is about unusual bipolar depression medication and not medication for mania is because the medications we have for mania are quite effective for most people. It is the bipolar depression that, typically, is very hard to treat. Additionally the two Food and Drug Administration (FDA)-approved bipolar depression treatments (quetiapine and an olanzapine/fluoxetine combination) tend to carry very serious side effects like weight gain, risk of diabetes including diabetic ketoacidosis and others. We also know that most people with bipolar disorder spend vastly more time in a depressed state than in a manic state.

According to Dr. Prakash Masand, CEO and founder of Global Medical Education, “Less than 30% of bipolar patients achieve remission that is maintained long term. There are great unmet needs in the treatment of bipolar depression. Innovative approaches are needed rather than ‘me-too’ agents that offer little incremental benefit.”

Dr. Masand notes the following are new, novel agents that look promising in the treatment of bipolar depression.

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What to Do When Someone Refuses to Take Their Medication – Treatment Noncompliance

It is an unfortunate truth that many mental illness patients won’t take their medications at one time or another. This is known as treatment noncompliance or treatment nonadherence, if you want to be a bit more politically correct.

And also unfortunate is the fact that when a person with a mental illness refuses to take their medication they almost inexorably get sicker. People with bipolar disorder who won’t take their medication, for example, often become manic and then wind up hurting themselves or someone else and end up in the hospital. And watching this happen, as a loved one, is extremely painful.

So is there anything you can do when a person refuses to take their medication? Is there anything you can do about treatment noncompliance?

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Under the Influence of Drugs – I Can Think Just Fine

I’m on Twitter. Not a surprise there. And I have a pretty active following there. Most of the people are fans, but a few aren’t. A few quite disagree with me and what I have to say. Which is fine. People can have their views.

And recently, I was tweeting along, minding my own business when someone said this to me:

and have you been on antidepressant, mind altering drugs all these years. Making choices while under the influence

My first reflex was to reply,

and have you been making choices all this time while being an ignorant, sanctimonious ass?

Sigh.

But I’ve heard through the grapevine that wouldn’t be professional. So I said nothing. If Mr. Twitter wants to judge me for taking medically prescribed medication, that’s his right. Even if it is a small-minded, uncompassionate, hateful thing to do.

And really, I have snarky answers for many of the asinine comments people make to me. However, I don’t tend to share them as it makes people all pissy. That being said, this particular comment hit a sore spot – being under the influence of brain-bending medications.

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Personal Story of Medication Noncompliance

It is politically incorrect to say medication “noncompliance.” I suppose this is because it gives the idea that the person taking medication is “complying” to some authority figure and not consciously making the decision on their own.

I get that. But whether you call it medication noncompliance or medication non-adherence, the result is the same – the person is not taking their medications as prescribed by a doctor.

And medication noncompliance can lead to devastating consequences not only in the short-term but in the long-term as well. One reader shares her experience in her own words.

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Are Psych Meds Addictive? – Antidepressants (Part 1)

Before I started taking psych meds, one of the major concerns I had was addiction.

I didn’t want to be an addict of any sort as I’m quite familiar with the horrors of addiction, having addicts in the family.[push]Will I get addicted to antidepressants?[/push]

And I knew people often took antidepressants for long periods of time, sometimes forever.

So weren’t these people addicted to antidepressants?

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Who Do You Trust for Mental Illness Medication Information?

As you might have noticed, I’ve been writing about bipolar and mental illness for a really long time. Seven years in internet time is a lifetime or so.

I Write About and Research Mental Illness

Trusting Mental Health SourcesAnd in all that time, in addition to the writing, I’ve been reading, or more commonly, researching mental illness. I’ve been looking up information on mental disorders, psychiatric medications, mental illness treatments, supplements and everything else of which you can think. This is because I like to be educated about my bipolar disorder and my healthcare and treatments. I often share that researched information because I think others should be educated about mental illness too. I strive to make anything I write accurate and provide links to reputable sources.

Who Do You Trust for Mental Illness Information?

But what information should you trust? Who should you trust for mental health information? Should you trust me, a random blogger? People on discussion groups? Information sites? Drug company sites? Doctor sites?

Pretty much, almost always, no.

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I write a three-time Web Health Award winning column for HealthyPlace called Breaking Bipolar.

Also, find my writings on The Huffington Post and my work for BPHope (BP Magazine).

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