How to Research Bipolar Disorder or another Mental Illness

Posted by Natasha Tracy | Jul 23, 2012

When you or someone you love is diagnosed with a mental illness like bipolar disorder, likely, you don’t know much about the mental illness outside of what the media and popular culture has told you. Unfortunately, these are not the best sources of information about bipolar disorder, depression, schizophrenia or other mental illnesses.

Mental Health Research

What is critical is that you take it upon yourself to research the mental illness so you can get the facts and not believe the fictions propagated about mental illness. If you’re here at the Bipolar Burble, and reading this, you’ve made an excellent start but I encourage you to continue with these other trusted research options.

Breaking Bipolar Reading Round-Up

Posted by Natasha Tracy | Dec 23, 2011

Happy holidays all.

I’m a pretty busy gal right now, so not a lot of time to write new material. I promise I’ll try to get to something new next week.

However, while you’re waiting, have you caught up on all your Breaking Bipolar articles? No? I didn’t think so. Here’s a run-down on some of what I’ve been doing over at HealthyPlace:

Last Minute Holiday Tips for the Bipolar – just published today. Here are four things you should know before you get any deeper into the holidays.
What 2011 Taught us About Mental Illness – a wrap-up of the top ten things research taught us about mental illness last year including: bipolar misdiagnosis, bipolar treatment success predictor, mania treatment comparison and antipsychotic information. Part one and part two.
You’re Narcissistic! Getting Over Insults – How one reader got to me even though I knew they shouldn’t have.
Celebrating Mental Health News – on why we should celebrate the good moments in mental illness.
How to Choose a Good Psychiatrist – one I’ve touched on here but in more detail.
Bipolar Disorder Thought Types – have you ever considered the odd types of thoughts you have a person with a mental illness? I have.
The Importance of Self-Care in Bipolar Disorder – tips on self-care plus a video.
Sexual Health and Bipolar Disorder – the sexual concerns of people with mental illness.

Drug Trials, Antidepressants and Placebo Effect – Is it Bad?

Posted by Natasha Tracy | Dec 12, 2011

When drug trials are conducted, the gold standard (and requirement for FDA approval) is a double-blind placebo-controlled study. In this kind of drug study participants are randomly assigned to receive either the medication or an inert (does nothing) pill known as a placebo. Neither the doctor not the patient knows whether they are getting the placebo or the real drug.

The study then compares what happens to those who received the real drug versus those who received the placebo and determines the efficacy of the real drug.

The Placebo Effect

This is critical because of something known as the “placebo effect.” The placebo effect is this odd scenario where people get better just because you give them a pill, even if the pill does nothing. Doctors and scientists don’t understand the placebo effect but not only will people get better on a placebo, but they will even experience side effects – something that isn’t possible given that the placebo is inert. But the brain is a powerful thing and something we don’t fully understand.

And one of the problems with antidepressants (and many medications) is that sometimes they aren’t better than the placebo. Additionally, sometimes when they are better than the placebo, it’s only by a small margin. Drug companies have to prove that their drug is statistically significantly better than a placebo in order to get FDA approval but even this statistically significant amount can be very small.

However, this isn’t a piece about how effective are when antidepressants are compared to placebos. This is a piece about how effective antidepressants are compared to no treatment.

No Evidence of the Effectiveness of Psychotherapy? – 3 New Things

Posted by Natasha Tracy | Sep 15, 2011

This week I learned three new things about psychotherapy and depression.

I’m a fan of psychotherapy for everyone. In fact, if we could get the mid-East folks to sit down for some good counselling, I think it would be more effective in bringing peace than anything you can do with a gun.

With that said, there are limitations to therapy and sometimes therapy is not all it’s cracked up to be. So this week, a look at three perspectives on psychotherapy:

Psychotherapy is no better than placebo in treating depression?
Which type of psychotherapy is better for depression?
How does psychotherapy change the brain?

New Antipsychiatry Discussion, L-Theanine, Rapid Cycling Markets – 3 New Things

Posted by Natasha Tracy | Sep 1, 2011

This week’s three new things include:

A new supplement that may help brain health and mental illness: l-theanine
A poor comparison between rapid cycling bipolar disorder and the financial markets
A new discussion of antipsychiatry

Linky-Madness, Drugging Children and Anxious Hat Makers – 3 New Things

Posted by Natasha Tracy | Aug 25, 2011

In my line of work I come across the most obscure information, which is why I love sharing it with you. This week’s three new things about mental illness include:

A weekly mental health link-party
How scientists want to drug children who might get a mental illness
How hat makers used to experience social phobia

How could you not want to know the details about that?

Five New Bipolar Depression Treatments You Don’t Know About – Part 2/2

Posted by Natasha Tracy | Jun 22, 2011

As I mentioned, people with bipolar type II spend 35X more time depressed than hypomanic, and yet there are very few treatments available.

As we discussed last time, the neurotransmitter glutamate and the inflammatory complex are two new, badly-needed areas of bipolar depression treatment research. Here are three additional bipolar depression treatment areas you probably don’t know about: diet, antioxidants and modafinil.

Depressed People Who Take Antidepressants Do Better Long-Term – Part 2

Posted by Natasha Tracy | May 16, 2011

As I mentioned last week, it’s very difficult to measure long-term outcomes of depression treatment due to the confounding depression variables like severity of depression, duration of depression, number of depressions and so on.

In short, the sicker you are, the more depressed you are, the more likely it is you’ll get treatment.

Antidepressant Treatment Outcomes Long-Term, A Study

I discussed the basic outcomes of this study: The association between antidepressant use and depression eight years later: A national cohort study by Colman et al. which tries to take these variables into account.

Colman et al. showed those who took antidepressants had better depression treatment outcomes than those who didn’t, eight years later, once confounding variables were taken into consideration.

I’ll now point out the strengths and weaknesses of this study as well as some other interesting tidbits shown or cited in the study. Oh, and I’ll give my opinion on what it all means.

Depressed People Who Take Antidepressants Do Better Long-Term

Posted by Natasha Tracy | May 12, 2011

Recently the controversy over long-term outcomes of those who use psychotropic medication has flared up again. Some people argue depression/bipolar/mental illness patients do the same, or better, when they don’t take psychiatric medications long-term. However, the statistics they use to assert this claim are often faulty.

A study from Calgary, Alberta, Canada (yes, we do research up here too) has attempted to fix some of the bias seen in other long-term depression treatment outcome statistics. I’ll cut to the chase for you:

Over the course of eight years people with depression who took antidepressants had better outcomes.